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Literature summary extracted from

  • Tezuka, T.; Someya, J.
    Purification and some properties of mercuric reductase from the organomercury-resistant Penicillium sp. MR-2 strain (1990), Agric. Biol. Chem., 54, 1551-1552.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.16.1.1 2-mercaptoethanol activates, optimal concentration is 3.3 mM Penicillium sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.16.1.1 0.0088
-
 Hg
-
 Penicillium sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.16.1.1 58000
-
 gel filtration Penicillium sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.16.1.1 Hg2+ + NADPH Penicillium sp. the enzyme is a key component of an organomercurial detoxification system Hg + NADP+ + H+
-
 ?
1.16.1.1 Hg2+ + NADPH Penicillium sp. MR-2 the enzyme is a key component of an organomercurial detoxification system Hg + NADP+ + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.16.1.1 Penicillium sp.
-
 MR-2 strain
-
1.16.1.1 Penicillium sp. MR-2
-
 MR-2 strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.16.1.1
-
 Penicillium sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.16.1.1 Hg + NADP+ + H+
-
 Penicillium sp. Hg2+ + NADPH
-
 r
1.16.1.1 Hg + NADP+ + H+
-
 Penicillium sp. MR-2 Hg2+ + NADPH
-
 r
1.16.1.1 Hg2+ + NADH very little activity with NADH Penicillium sp. Hg + NAD+ + H+
-
 ?
1.16.1.1 Hg2+ + NADH very little activity with NADH Penicillium sp. MR-2 Hg + NAD+ + H+
-
 ?
1.16.1.1 Hg2+ + NADPH
-
 Penicillium sp. Hg + NADP+ + H+
-
 ?
1.16.1.1 Hg2+ + NADPH the enzyme is a key component of an organomercurial detoxification system Penicillium sp. Hg + NADP+ + H+
-
 ?
1.16.1.1 Hg2+ + NADPH
-
 Penicillium sp. MR-2 Hg + NADP+ + H+
-
 ?
1.16.1.1 Hg2+ + NADPH the enzyme is a key component of an organomercurial detoxification system Penicillium sp. MR-2 Hg + NADP+ + H+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.16.1.1 monomer 1 * 58000, SDS-PAGE Penicillium sp.

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.16.1.1 34
-
-
 Penicillium sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.16.1.1 7.5 8
-
 Penicillium sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.16.1.1 FAD activity is dependent upon Penicillium sp.
1.16.1.1 NADH very little activity Penicillium sp.
1.16.1.1 NADPH
-
 Penicillium sp.