EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.17.4.1 | cytoplasm | enzyme from Novikoff hepatoma tumor cells is associated with a smooth membrane component of the cytoplasm | Rattus norvegicus | 5737 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | Rattus norvegicus | critical and rate-controlling step in pathway leading to DNA synthesis and cell replication | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | Rattus norvegicus | thioredoxin is the physiological reductant | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.4.1 | Rattus norvegicus | - |
Morris hepatoma cells | - |
1.17.4.1 | Rattus norvegicus | - |
Novikoff hepatoma cells | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.17.4.1 | additional information | - |
strong increase of specific activity during growth of Novikoff hepatoma cells | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | - |
Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | critical and rate-controlling step in pathway leading to DNA synthesis and cell replication | Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | thioredoxin is the physiological reductant | Rattus norvegicus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
? |