BRENDA - Enzyme Database

Effect of hydroxyurea on T4 ribonucleotide reductase

Berglund, O.; Sjoberg, B.M.; J. Biol. Chem. 254, 253-254 (1979)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.17.4.1
Hydroxyurea
0.01-0.03 mM, 50% inhibition, 0.2 mM, complete inhibition
Escherichia virus T4
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.17.4.1
Escherichia virus T4
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.1
ribonucleoside diphosphate + reduced thioredoxin
-
437956
Escherichia virus T4
2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O
-
437956
Escherichia virus T4
ir
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.17.4.1
Hydroxyurea
0.01-0.03 mM, 50% inhibition, 0.2 mM, complete inhibition
Escherichia virus T4
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.1
ribonucleoside diphosphate + reduced thioredoxin
-
437956
Escherichia virus T4
2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O
-
437956
Escherichia virus T4
ir