BRENDA - Enzyme Database

Vaccinia virus induces ribonucleotide reductase in primate cells

Slabaugh, M.B.; Johnson, T.L.; Mathews, C.K.; J. Virol. 52, 507-514 (1984)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.17.4.1
dATP
inhibition of CDP reduction
Platyrrhini
1.17.4.1
dTTP
inhibition of CDP reduction
Platyrrhini
1.17.4.1
EDTA
1 mM, 72% inhibition
Platyrrhini
1.17.4.1
Hydroxyurea
-
Platyrrhini
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.17.4.1
Platyrrhini
-
monkey kidney cells BSC-40 induced by vaccina virus strain WR, activity may be virally encoded
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.17.4.1
BSC-40 cell
-
Platyrrhini
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.1
ribonucleoside diphosphate + reduced thioredoxin
-
437922
Platyrrhini
2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O
-
437922
Platyrrhini
ir
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.17.4.1
dATP
inhibition of CDP reduction
Platyrrhini
1.17.4.1
dTTP
inhibition of CDP reduction
Platyrrhini
1.17.4.1
EDTA
1 mM, 72% inhibition
Platyrrhini
1.17.4.1
Hydroxyurea
-
Platyrrhini
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.17.4.1
BSC-40 cell
-
Platyrrhini
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.1
ribonucleoside diphosphate + reduced thioredoxin
-
437922
Platyrrhini
2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O
-
437922
Platyrrhini
ir