EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.17.4.2 | 0.017 | - |
dGTP | - |
Lactobacillus leichmannii | |
1.17.4.2 | 0.06 | - |
adenosylcobalamin | - |
Lactobacillus leichmannii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Escherichia coli | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Lactobacillus leichmannii | catalyzes the rate-determining step in DNA biosynthesis | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.4.2 | Escherichia coli | - |
- |
- |
1.17.4.2 | Lactobacillus leichmannii | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.2 | GTP + reduced thioredoxin | - |
Lactobacillus leichmannii | dGTP + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Escherichia coli | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | catalyzes the rate-determining step in DNA biosynthesis | Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.17.4.2 | RNR | - |
Lactobacillus leichmannii |
1.17.4.2 | RTPR | - |
Lactobacillus leichmannii |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Lactobacillus leichmannii |