BRENDA - Enzyme Database

Cobamides and ribonucleotide reduction. I. Cobamide stimulation of ribonucleotide reduction in extracts of Lactobacillus leichmannii

Bakley, R.L.; J. Biol. Chem. 240, 2173-2180 (1965)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
1.17.4.2
2',5'-dideoxyadenosylcobalamin anilide
-
Lactobacillus leichmannii
1.17.4.2
2-mercaptoethanol
-
Lactobacillus leichmannii
1.17.4.2
5'-deoxyadenosylcobalamin
-
Lactobacillus leichmannii
1.17.4.2
5'-deoxyadenosylcobalamin anilide
-
Lactobacillus leichmannii
1.17.4.2
5'-deoxyuridylcobalamin
-
Lactobacillus leichmannii
1.17.4.2
cobinamide
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin anilide
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin dibasic acid
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin ethylamide
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin monobasic acid
-
Lactobacillus leichmannii
1.17.4.2
ethyl cobalamin
-
Lactobacillus leichmannii
1.17.4.2
hydroxocobalamin
-
Lactobacillus leichmannii
1.17.4.2
hydroxocobalamin methylamide
-
Lactobacillus leichmannii
1.17.4.2
methyl cobalamin
-
Lactobacillus leichmannii
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.17.4.2
ribonucleoside triphosphate + reduced thioredoxin + H2O
Lactobacillus leichmannii
-
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
-
r
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.17.4.2
Lactobacillus leichmannii
-
mutant of strain ATCC 4797, produced during many years of transfers on litmus milk
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.2
CTP + reduced thioredoxin
-
437887
Lactobacillus leichmannii
dCTP + oxidized thioredoxin + H2O
-
-
-
?
1.17.4.2
ribonucleoside triphosphate + reduced thioredoxin
-
437887
Lactobacillus leichmannii
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
-
-
r
1.17.4.2
ribonucleoside triphosphate + reduced thioredoxin + H2O
-
437887
Lactobacillus leichmannii
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
-
-
r
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
1.17.4.2
2',5'-dideoxyadenosylcobalamin anilide
-
Lactobacillus leichmannii
1.17.4.2
2-mercaptoethanol
-
Lactobacillus leichmannii
1.17.4.2
5'-deoxyadenosylcobalamin
-
Lactobacillus leichmannii
1.17.4.2
5'-deoxyadenosylcobalamin anilide
-
Lactobacillus leichmannii
1.17.4.2
5'-deoxyuridylcobalamin
-
Lactobacillus leichmannii
1.17.4.2
cobinamide
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin anilide
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin dibasic acid
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin ethylamide
-
Lactobacillus leichmannii
1.17.4.2
cyanocobalamin monobasic acid
-
Lactobacillus leichmannii
1.17.4.2
ethyl cobalamin
-
Lactobacillus leichmannii
1.17.4.2
hydroxocobalamin
-
Lactobacillus leichmannii
1.17.4.2
hydroxocobalamin methylamide
-
Lactobacillus leichmannii
1.17.4.2
methyl cobalamin
-
Lactobacillus leichmannii
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.17.4.2
ribonucleoside triphosphate + reduced thioredoxin + H2O
Lactobacillus leichmannii
-
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
-
r
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.2
CTP + reduced thioredoxin
-
437887
Lactobacillus leichmannii
dCTP + oxidized thioredoxin + H2O
-
-
-
?
1.17.4.2
ribonucleoside triphosphate + reduced thioredoxin
-
437887
Lactobacillus leichmannii
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
-
-
r
1.17.4.2
ribonucleoside triphosphate + reduced thioredoxin + H2O
-
437887
Lactobacillus leichmannii
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
-
-
-
r