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Literature summary extracted from
- Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast (1953), J. Biol. Chem., 201, 629-637.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.1.4 | 0.014 | - |
NADP+ | - |
Saccharomyces cerevisiae |  |
| 1.2.1.4 | 0.035 | - |
acetaldehyde | - |
Saccharomyces cerevisiae | |
| 1.2.1.4 | 2.2 | - |
glycolaldehyde | - |
Saccharomyces cerevisiae | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.4 | Ba2+ | activates | Saccharomyces cerevisiae | |
| 1.2.1.4 | Ca2+ | activates | Saccharomyces cerevisiae | |
| 1.2.1.4 | Mg2+ | activates | Saccharomyces cerevisiae | |
| 1.2.1.4 | Mn2+ | activates | Saccharomyces cerevisiae | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.1.4 | Saccharomyces cerevisiae | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.2.1.4 | - |
Saccharomyces cerevisiae |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.4 | additional information | - |
- |
Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.1.4 | acetaldehyde + NADP+ + H2O | - |
Saccharomyces cerevisiae | acetate + NADPH + H+ | - |
? | |
| 1.2.1.4 | formaldehyde + NADP+ + H2O | - |
Saccharomyces cerevisiae | formate + NADPH + H+ | - |
? | |
| 1.2.1.4 | glycolaldehyde + NADP+ + H2O | - |
Saccharomyces cerevisiae | glycolate + NADPH + H+ | - |
? | |
| 1.2.1.4 | propanal + NADP+ + H2O | - |
Saccharomyces cerevisiae | propionate + NADPH + H+ | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.4 | 7.5 | 8 | - |
Saccharomyces cerevisiae |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.4 | 6.8 | 8.7 | about 50% of maximal activity at pH 6.8 and 8.0 | Saccharomyces cerevisiae |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.4 | NADP+ | 0.1-0.4% of the activity with NADP+ | Saccharomyces cerevisiae | |
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