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Literature summary extracted from

  • Dean, B.; Bartley, W.
    Oxaloacetate decarboxylases of rat liver (1973), Biochem. J., 135, 667-672.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.112 citrate 50% inhibition of mitochondrial enzyme at 4.5 mM Rattus norvegicus
4.1.1.112 coenzyme A 50% inhibition of mitochondrial enzyme at 0.05 mM Rattus norvegicus
4.1.1.112 phosphoenolpyruvate 50% inhibition of mitochondrial enzyme at 28 mM Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.112 0.15
-
 oxaloacetate
-
 Rattus norvegicus
4.1.1.112 0.23
-
 oxaloacetate mitochondrial enzyme Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.112 cytoplasm differs from mitochondrial enzyme Rattus norvegicus 5737
-
4.1.1.112 microsome
-
 Rattus norvegicus
-
-
4.1.1.112 mitochondrion differs from cytoplasmic enzyme Rattus norvegicus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.112 Mg2+ only cytoplasmic enzyme Rattus norvegicus
4.1.1.112 Mn2+ only cytoplasmic enzyme Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.112 oxaloacetate Rattus norvegicus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.112 Rattus norvegicus
-
 rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.112 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.112 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.112 Oxaloacetate
-
 Rattus norvegicus Pyruvate + CO2
-
 ?
4.1.1.112 oxaloacetate
-
 Rattus norvegicus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.112 30
-
 enzyme assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.112 5
-
 cytoplasmic enzyme Rattus norvegicus
4.1.1.112 9.5
-
 mitochondrial enzyme Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.112 7 10
-
 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.1.1.112 28
-
 phosphoenolpyruvate mitochondrial enzyme Rattus norvegicus