Any feedback?
Literature summary extracted from
- Preparation, characterization, and reconstitution of oxaloacetate decarboxylase from Klebsiella aerogenes, a sodium pump (1986), Methods Enzymol., 125, 530-540.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.4.2 | 2-Oxomalonate | - |
Klebsiella aerogenes |  |
| 7.2.4.2 | Avidin | - |
Klebsiella aerogenes | |
| 7.2.4.2 | glyoxylate | - |
Klebsiella aerogenes | |
| 7.2.4.2 | L-malate | - |
Klebsiella aerogenes | |
| 7.2.4.2 | oxalate | competitive for oxaloacetate, Ki: 0.0038 mM | Klebsiella aerogenes | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 7.2.4.2 | 0.15 | - |
oxaloacetate | - |
Klebsiella aerogenes | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.2.4.2 | membrane | - |
Klebsiella aerogenes | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.4.2 | Na+ | Km: 1 mM | Klebsiella aerogenes | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 7.2.4.2 | 12000 | - |
1 * 65000 + 1 * 34000 + 1 * 12000 alpha,beta,gamma, SDS-PAGE, subunits carry different functions | Klebsiella aerogenes |
| 7.2.4.2 | 34000 | - |
1 * 65000 + 1 * 34000 + 1 * 12000 alpha,beta,gamma, SDS-PAGE, subunits carry different functions | Klebsiella aerogenes |
| 7.2.4.2 | 65000 | - |
1 * 65000 + 1 * 34000 + 1 * 12000 alpha,beta,gamma, SDS-PAGE, subunits carry different functions | Klebsiella aerogenes |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.4.2 | oxaloacetate | Klebsiella aerogenes | decarboxylation energy used for active Na+ transport | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.2.4.2 | Klebsiella aerogenes | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.2.4.2 | - |
Klebsiella aerogenes |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 7.2.4.2 | oxaloacetate = pyruvate + CO2 | pyruvate + CO2 = oxaloacetae | Klebsiella aerogenes |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 7.2.4.2 | additional information | - |
- |
Klebsiella aerogenes |
| 7.2.4.2 | 46.3 | - |
- |
Klebsiella aerogenes |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.4.2 | additional information | transmembrane transport of Na+ | Klebsiella aerogenes | ? | - |
? | |
| 7.2.4.2 | Oxaloacetate | - |
Klebsiella aerogenes | Pyruvate + CO2 | - |
? | |
| 7.2.4.2 | oxaloacetate | decarboxylation energy used for active Na+ transport | Klebsiella aerogenes | ? | - |
? | |
| 7.2.4.2 | Pyruvate + CO2 | - |
Klebsiella aerogenes | Oxaloacetate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.2.4.2 | trimer | 1 * 65000 + 1 * 34000 + 1 * 12000 alpha,beta,gamma, SDS-PAGE, subunits carry different functions | Klebsiella aerogenes |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 7.2.4.2 | 25 | - |
enzyme assay at | Klebsiella aerogenes |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 7.2.4.2 | 6.5 | 7.5 | - |
Klebsiella aerogenes |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.4.2 | biotin | about 1 mol bound per alpha-chain | Klebsiella aerogenes | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
