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Literature summary extracted from

  • Zhu, M.Y.; Juorio, A.V.
    Aromatic L-amino acid decarboxylase: biological characterization and functional role (1995), Gen. Pharmacol., 26, 681-696.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.28 additional information
-
additional information
-
Cavia porcellus
4.1.1.28 additional information
-
additional information
-
Homo sapiens
4.1.1.28 additional information
-
additional information
-
Rattus norvegicus
4.1.1.28 additional information
-
additional information
-
Sus scrofa
4.1.1.28 additional information
-
additional information
-
Bos taurus
4.1.1.28 additional information
-
additional information
-
Xenopus laevis
4.1.1.28 0.4
-
3,4-dihydroxyphenylalanine
-
Cavia porcellus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.28 additional information Cavia porcellus the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C ?
-
?
4.1.1.28 additional information Homo sapiens the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C ?
-
?
4.1.1.28 additional information Rattus norvegicus the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C ?
-
?
4.1.1.28 additional information Sus scrofa the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C ?
-
?
4.1.1.28 additional information Bos taurus the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.28 Bos taurus
-
-
-
4.1.1.28 Cavia porcellus
-
-
-
4.1.1.28 Homo sapiens
-
-
-
4.1.1.28 Rattus norvegicus
-
-
-
4.1.1.28 Sus scrofa
-
-
-
4.1.1.28 Xenopus laevis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.28 adrenal gland
-
Rattus norvegicus
-
4.1.1.28 adrenal gland adrenal medulla Bos taurus
-
4.1.1.28 brain
-
Rattus norvegicus
-
4.1.1.28 brain
-
Sus scrofa
-
4.1.1.28 brain brain stem Homo sapiens
-
4.1.1.28 brain brain stem Bos taurus
-
4.1.1.28 corpus striatum
-
Rattus norvegicus
-
4.1.1.28 corpus striatum
-
Bos taurus
-
4.1.1.28 kidney
-
Cavia porcellus
-
4.1.1.28 kidney
-
Homo sapiens
-
4.1.1.28 kidney
-
Sus scrofa
-
4.1.1.28 liver
-
Rattus norvegicus
-
4.1.1.28 oocyte
-
Xenopus laevis
-
4.1.1.28 PC-12 cell
-
Rattus norvegicus
-
4.1.1.28 pineal gland
-
Rattus norvegicus
-
4.1.1.28 pineal gland
-
Bos taurus
-
4.1.1.28 retina
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.28 3,4-Dihydroxyphenylalanine
-
Cavia porcellus 3-Hydroxytyramine + CO2
-
?
4.1.1.28 3,4-Dihydroxyphenylalanine
-
Homo sapiens 3-Hydroxytyramine + CO2
-
?
4.1.1.28 3,4-Dihydroxyphenylalanine
-
Rattus norvegicus 3-Hydroxytyramine + CO2
-
?
4.1.1.28 3,4-Dihydroxyphenylalanine
-
Sus scrofa 3-Hydroxytyramine + CO2
-
?
4.1.1.28 3,4-Dihydroxyphenylalanine
-
Bos taurus 3-Hydroxytyramine + CO2
-
?
4.1.1.28 additional information the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C Cavia porcellus ?
-
?
4.1.1.28 additional information the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C Homo sapiens ?
-
?
4.1.1.28 additional information the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C Rattus norvegicus ?
-
?
4.1.1.28 additional information the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C Sus scrofa ?
-
?
4.1.1.28 additional information the enzyme is responsible for the decarboxylation step in both the catecholamine and the indolamine synthetic pathways. The enzyme is regulated by a short term mechanism that may involve activation of adenyl cyclase or protein kinase C Bos taurus ?
-
?
4.1.1.28 Tyr
-
Cavia porcellus ?
-
?
4.1.1.28 Tyr
-
Sus scrofa ?
-
?