EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.28 | pyridoxal 5'-phosphate | inhibition at high concentrations, stimulation at lower concentration | Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.28 | 0.14 | - |
3,4-dihydroxyphenylalanine | brain enzyme | Bos taurus | |
4.1.1.28 | 0.16 | - |
3,4-dihydroxyphenylalanine | - |
Bos taurus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.1.1.28 | 50000 | - |
2 * 50000, SDS-PAGE | Bos taurus |
4.1.1.28 | 100000 | - |
gel filtration | Bos taurus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.28 | Bos taurus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.1.28 | affinity chromatography using monoclonal antibody | Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.1.1.28 | adrenal gland | adrenal medulla | Bos taurus | - |
4.1.1.28 | brain | - |
Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.1.1.28 | 0.043 | - |
brain enzyme | Bos taurus |
4.1.1.28 | 0.19 | - |
adrenal medulla enzyme | Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.28 | 3,4-Dihydroxyphenylalanine | - |
Bos taurus | 3-Hydroxytyramine + CO2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.1.1.28 | dimer | 2 * 50000, SDS-PAGE | Bos taurus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.1.1.28 | 7.2 | - |
- |
Bos taurus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
4.1.1.28 | 5 | 8.5 | pH 5.0: about 45% of maximal activity, pH 8.5: about 45% of maximal activity, adrenal medulla enzyme | Bos taurus |
4.1.1.28 | 5.5 | 8.5 | pH 5.5: about 55% of maximal activity, pH 8.5: about 35% of maximal activity, brain enzyme | Bos taurus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.28 | pyridoxal 5'-phosphate | stimulates, high concentrations inhibit | Bos taurus |