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Literature summary extracted from

  • Li, G.; Regunathan, S.; Reis, D.J.
    Agmatine is synthesized by a mitochondrial arginine decarboxylase in rat brain (1995), Ann. N. Y. Acad. Sci., 763, 325-329.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.19 L-Gln
-
 Rattus norvegicus
4.1.1.19 L-Lys
-
 Rattus norvegicus
4.1.1.19 NG-methylarginine
-
 Rattus norvegicus
4.1.1.19 NG-Nitroarginine
-
 Rattus norvegicus
4.1.1.19 Orn L-Orn Rattus norvegicus
4.1.1.19 putrescine
-
 Rattus norvegicus
4.1.1.19 spermidine
-
 Rattus norvegicus
4.1.1.19 spermine
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.19 0.75
-
 L-Arg
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.19 mitochondrion highly if not exclusively associated with mitochondrial membrane Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.19 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.19 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.19 L-arginine
-
 Rattus norvegicus agmatine + CO2
-
 ?
4.1.1.19 L-Orn
-
 Rattus norvegicus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.19 30
-
-
 Rattus norvegicus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.19 30 37 30°C: maximal activity, 37°C: about 35% of maximal activity Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.19 8.3
-
-
 Rattus norvegicus