Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • McCann, P.P.; Bacchi, C.J.; Hanson, W.L.; Nathan, H.C.; Hutner, S.H.; Sjoerdsma, A.
    Methods for the study of the treatment of protozoan diseases by inhibitors of ornithine decarboxylase (1983), Methods Enzymol., 94, 209-213.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.17 alpha-DL-difluoromethylornithine irreversibel Eimeria tenella
4.1.1.17 alpha-DL-difluoromethylornithine irreversibel Trypanosoma brucei
4.1.1.17 additional information treatment of protozoan diseases by inhibitors of ornithine decarboxylase Eimeria tenella
4.1.1.17 additional information treatment of protozoan diseases by inhibitors of ornithine decarboxylase Trypanosoma brucei

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.17 L-Orn Trypanosoma brucei first step in polyamine biosynthesis ?
-
 ?
4.1.1.17 L-Orn Eimeria tenella first step in polyamine biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Eimeria tenella
-
-
-
4.1.1.17 Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-Orn
-
 Trypanosoma brucei Putrescine + CO2
-
 ?
4.1.1.17 L-Orn
-
 Eimeria tenella Putrescine + CO2
-
 ?
4.1.1.17 L-Orn first step in polyamine biosynthesis Trypanosoma brucei ?
-
 ?
4.1.1.17 L-Orn first step in polyamine biosynthesis Eimeria tenella ?
-
 ?