BRENDA - Enzyme Database

Biosynthetic and biodegradative ornithine and arginine decarboxylases from Escherichia coli

Morris, D.R.; Boeker, E.A.; Methods Enzymol. 94, 125-134 (1983)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.1.17
3.6
-
L-Orn
degradative ornithine decarboxylase
Escherichia coli
4.1.1.17
5.6
-
L-Orn
biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
additional information
-
additional information
-
Escherichia coli
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.1.1.17
80000
-
2 * 80000, degradative ornithine decarboxylase
Escherichia coli
4.1.1.17
81000
-
2 * 81000, biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
74000
-
4 * 74000, biosynthetic arginine decarboxylase
Escherichia coli
4.1.1.19
82000
-
10 * or 1 * 82000, degradative arginine decarboxylase; 2 * or 10 * 82000, degradative arginine decarboxylase
Escherichia coli
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.1.19
L-Arg
Escherichia coli
2 enzyme forms: a biosynthetic arginine decarboxylase and a degradative arginine decarboxylase. The physiological role of the degradative arginine decarboxylase possibly is the regulation of the environmental pH
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.1.17
Escherichia coli
-
-
-
4.1.1.19
Escherichia coli
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.1.1.17
a biosynthetic ornithine decarboxylase and a degradative ornithine decarboxylase
Escherichia coli
4.1.1.19
biosynthetic arginine decarboxylase and synthetic arginine decarboxylase
Escherichia coli
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4.1.1.17
99
-
biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.17
130
-
degradative ornithine decarboxylase
Escherichia coli
4.1.1.19
16.4
-
biosynthetic arginine decarboxylase
Escherichia coli
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.17
L-Orn
-
4019
Escherichia coli
Putrescine + CO2
-
-
-
-
4.1.1.19
L-Arg
2 enzyme forms: a biosynthetic arginine decarboxylase and a degradative arginine decarboxylase. The physiological role of the degradative arginine decarboxylase possibly is the regulation of the environmental pH
4019
Escherichia coli
?
-
-
-
-
4.1.1.19
L-arginine
-
4019
Escherichia coli
agmatine + CO2
-
4019
Escherichia coli
-
Subunits
EC Number
Subunits
Commentary
Organism
4.1.1.17
dimer
2 * 80000, degradative ornithine decarboxylase; 2 * 81000, biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
decamer
10 * or 1 * 82000, degradative arginine decarboxylase
Escherichia coli
4.1.1.19
dimer
2 * or 10 * 82000, degradative arginine decarboxylase
Escherichia coli
4.1.1.19
tetramer
4 * 74000, biosynthetic arginine decarboxylase
Escherichia coli
Turnover Number [1/s]
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
4.1.1.17
additional information
-
additional information
-
Escherichia coli
4.1.1.19
additional information
-
additional information
-
Escherichia coli
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4.1.1.17
6.9
-
degradative ornithine decarboxylase
Escherichia coli
4.1.1.17
8.3
-
biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
5.2
-
degradative arginine decarboxylase
Escherichia coli
4.1.1.19
8.4
-
biosynthetic arginine decarboxylase
Escherichia coli
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
4.1.1.17
pyridoxal 5'-phosphate
cofactor
Escherichia coli
4.1.1.19
pyridoxal 5'-phosphate
stimulates
Escherichia coli
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
4.1.1.17
pyridoxal 5'-phosphate
cofactor
Escherichia coli
4.1.1.19
pyridoxal 5'-phosphate
stimulates
Escherichia coli
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.1.17
3.6
-
L-Orn
degradative ornithine decarboxylase
Escherichia coli
4.1.1.17
5.6
-
L-Orn
biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
additional information
-
additional information
-
Escherichia coli
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.1.1.17
80000
-
2 * 80000, degradative ornithine decarboxylase
Escherichia coli
4.1.1.17
81000
-
2 * 81000, biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
74000
-
4 * 74000, biosynthetic arginine decarboxylase
Escherichia coli
4.1.1.19
82000
-
10 * or 1 * 82000, degradative arginine decarboxylase; 2 * or 10 * 82000, degradative arginine decarboxylase
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.1.19
L-Arg
Escherichia coli
2 enzyme forms: a biosynthetic arginine decarboxylase and a degradative arginine decarboxylase. The physiological role of the degradative arginine decarboxylase possibly is the regulation of the environmental pH
?
-
-
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.1.1.17
a biosynthetic ornithine decarboxylase and a degradative ornithine decarboxylase
Escherichia coli
4.1.1.19
biosynthetic arginine decarboxylase and synthetic arginine decarboxylase
Escherichia coli
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4.1.1.17
99
-
biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.17
130
-
degradative ornithine decarboxylase
Escherichia coli
4.1.1.19
16.4
-
biosynthetic arginine decarboxylase
Escherichia coli
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.17
L-Orn
-
4019
Escherichia coli
Putrescine + CO2
-
-
-
-
4.1.1.19
L-Arg
2 enzyme forms: a biosynthetic arginine decarboxylase and a degradative arginine decarboxylase. The physiological role of the degradative arginine decarboxylase possibly is the regulation of the environmental pH
4019
Escherichia coli
?
-
-
-
-
4.1.1.19
L-arginine
-
4019
Escherichia coli
agmatine + CO2
-
4019
Escherichia coli
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
4.1.1.17
dimer
2 * 80000, degradative ornithine decarboxylase; 2 * 81000, biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
decamer
10 * or 1 * 82000, degradative arginine decarboxylase
Escherichia coli
4.1.1.19
dimer
2 * or 10 * 82000, degradative arginine decarboxylase
Escherichia coli
4.1.1.19
tetramer
4 * 74000, biosynthetic arginine decarboxylase
Escherichia coli
Turnover Number [1/s] (protein specific)
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
4.1.1.17
additional information
-
additional information
-
Escherichia coli
4.1.1.19
additional information
-
additional information
-
Escherichia coli
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4.1.1.17
6.9
-
degradative ornithine decarboxylase
Escherichia coli
4.1.1.17
8.3
-
biosynthetic ornithine decarboxylase
Escherichia coli
4.1.1.19
5.2
-
degradative arginine decarboxylase
Escherichia coli
4.1.1.19
8.4
-
biosynthetic arginine decarboxylase
Escherichia coli