Literature summary extracted from

Span, P.N.; Smals, A.G.; Sweep, C.G.; Benraad, T.J.
Rat steroid 5alpha-reductase kinetic characteristics: extreme pH-dependancy of the type II isozyme in prostate and epididymis homogenates (1995), J. Steroid Biochem. Mol. Biol., 54, 185-192.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.3.1.22	0.0011	-	testosterone	prostrate homogenate at pH 7	Rattus norvegicus
1.3.1.22	0.0025	-	testosterone	epidymis homogenate at pH 4.5	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.1.22	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.3.1.22	epididymis	-	Rattus norvegicus	-
1.3.1.22	prostate gland	-	Rattus norvegicus	-

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.3.1.22	5	-	isozyme 2, high substrate concentration	Rattus norvegicus
1.3.1.22	5.5	-	isozyme 2, low substrate concentration, efficiency optimum Vmax/Km	Rattus norvegicus

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Release 2023.1 (January 2023)