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Literature summary extracted from
- Degradative acetolactate synthase of Bacillus subtilis: purification and properties (1975), J. Bacteriol., 121, 917-922.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.2.1.6 | acetate | stimulates | Bacillus subtilis |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.2.1.6 | phosphate | inhibits activity of enzyme assayed in acetate buffer | Bacillus subtilis | |
| 2.2.1.6 | SO42- | competitive when assayed in phosphate buffer, mixed type, when assayed in acetate buffer | Bacillus subtilis | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.2.1.6 | 13 | - |
pyruvate | - |
Bacillus subtilis | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 2.2.1.6 | 250000 | - |
gel filtration | Bacillus subtilis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.2.1.6 | pyruvate | Bacillus subtilis | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.2.1.6 | Bacillus subtilis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 2.2.1.6 | - |
Bacillus subtilis |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 2.2.1.6 | 8.28 | - |
- |
Bacillus subtilis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.2.1.6 | pyruvate | - |
Bacillus subtilis | 2-acetolactate + CO2 | - |
? | |
| 2.2.1.6 | pyruvate | - |
Bacillus subtilis | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.2.1.6 | 5.8 | - |
acetate buffer | Bacillus subtilis |
| 2.2.1.6 | 7 | - |
phosphate buffer | Bacillus subtilis |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.2.1.6 | 6 | 8 | pH 6.0: about 55% of maximal activity, pH 8.0: about 50% of maximal activity | Bacillus subtilis |
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