EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.6 | Ile | no inhibition | Methanococcus aeolicus | |
2.2.1.6 | Ile | - |
Methanococcus maripaludis | |
2.2.1.6 | Ile | - |
Methanococcus voltae | |
2.2.1.6 | Leu | no inhibition | Methanococcus aeolicus | |
2.2.1.6 | Leu | - |
Methanococcus maripaludis | |
2.2.1.6 | Leu | no inhibition | Methanococcus voltae | |
2.2.1.6 | Val | feed-back inhibition | Methanococcus aeolicus | |
2.2.1.6 | Val | feed-back inhibition | Methanococcus maripaludis | |
2.2.1.6 | Val | feed-back inhibition | Methanococcus voltae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.2.1.6 | 0.5 | - |
pyruvate | - |
Methanococcus voltae | |
2.2.1.6 | 2.3 | - |
pyruvate | - |
Methanococcus aeolicus | |
2.2.1.6 | 4.2 | - |
pyruvate | - |
Methanococcus maripaludis |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.6 | Mg2+ | strong requirement | Methanococcus aeolicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.2.1.6 | Methanococcus aeolicus | - |
- |
- |
2.2.1.6 | Methanococcus maripaludis | - |
- |
- |
2.2.1.6 | Methanococcus voltae | - |
- |
- |
2.2.1.6 | Methanothermococcus thermolithotrophicus | - |
- |
- |
EC Number | Oxidation Stability | Organism |
---|---|---|
2.2.1.6 | 10% O2, 37°C, 30 min, 90% loss of activity | Methanococcus aeolicus |
2.2.1.6 | 10% O2, 37°C, 30 min, 90% loss of activity | Methanococcus maripaludis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.2.1.6 | pyruvate | - |
Methanothermococcus thermolithotrophicus | 2-acetolactate + CO2 | - |
? | |
2.2.1.6 | pyruvate | - |
Methanococcus aeolicus | 2-acetolactate + CO2 | - |
? | |
2.2.1.6 | pyruvate | - |
Methanococcus maripaludis | 2-acetolactate + CO2 | - |
? | |
2.2.1.6 | pyruvate | - |
Methanococcus voltae | 2-acetolactate + CO2 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.6 | FAD | - |
Methanococcus aeolicus | |
2.2.1.6 | thiamine diphosphate | required as cofactor | Methanothermococcus thermolithotrophicus | |
2.2.1.6 | thiamine diphosphate | required as cofactor | Methanococcus aeolicus | |
2.2.1.6 | thiamine diphosphate | required as cofactor | Methanococcus maripaludis | |
2.2.1.6 | thiamine diphosphate | required as cofactor | Methanococcus voltae | |
2.2.1.6 | thiamine diphosphate | required after dialysis | Methanococcus aeolicus | |
2.2.1.6 | thiamine diphosphate | required after dialysis | Methanococcus maripaludis | |
2.2.1.6 | thiamine diphosphate | required after dialysis | Methanococcus voltae | |
2.2.1.6 | thiamine diphosphate | Km: 0.0033 mM | Methanococcus maripaludis | |
2.2.1.6 | thiamine diphosphate | Km: 0.0031 mM | Methanococcus voltae |