EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.12.2.1 | CO | reversible | Desulfovibrio desulfuricans | |
1.12.2.1 | CO | reversible | Desulfovibrio vulgaris | |
1.12.2.1 | CO | - |
Megalodesulfovibrio gigas | |
1.12.2.1 | O2 | reversible inactivation | Desulfovibrio desulfuricans |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.12.2.1 | membrane | bound to | Desulfovibrio desulfuricans | 16020 | - |
1.12.2.1 | periplasm | - |
Desulfovibrio desulfuricans | - |
- |
1.12.2.1 | periplasm | - |
Megalodesulfovibrio gigas | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.12.2.1 | Iron | nonheme iron protein | Megalodesulfovibrio gigas | |
1.12.2.1 | Iron | 12.5 gatom nonheme iron and 11.5 gatom of acid-labile sulfide per mol, arranged in at least two Fe4S4 clusters of the ferredoxin type | Desulfovibrio vulgaris | |
1.12.2.1 | Iron | presence of a three-iron center | Desulfovibrio desulfuricans | |
1.12.2.1 | Iron | 11-12 gatom of nonheme iron per molecule | Megalodesulfovibrio gigas | |
1.12.2.1 | Nickel | - |
Desulfovibrio desulfuricans | |
1.12.2.1 | Nickel | 1 gatom of nickel per molecule | Megalodesulfovibrio gigas | |
1.12.2.1 | Nickel | purified enzyme contains variable amounts of nickel, ranging from 0.1 to 0.6 gatom per mol of enzyme | Desulfovibrio vulgaris |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.12.2.1 | 26000 | - |
x * 26000 + x * 62000 | Megalodesulfovibrio gigas |
1.12.2.1 | 58000 | - |
- |
Desulfovibrio desulfuricans |
1.12.2.1 | 62000 | - |
x * 26000 + x * 62000 | Megalodesulfovibrio gigas |
1.12.2.1 | 89500 | - |
- |
Megalodesulfovibrio gigas |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.12.2.1 | Desulfovibrio desulfuricans | - |
Norway 4 | - |
1.12.2.1 | Desulfovibrio desulfuricans Norway 4 | - |
Norway 4 | - |
1.12.2.1 | Desulfovibrio vulgaris | - |
Hildenborough | - |
1.12.2.1 | Desulfovibrio vulgaris Hildenborough | - |
Hildenborough | - |
1.12.2.1 | Megalodesulfovibrio gigas | - |
- |
- |
EC Number | Oxidation Stability | Organism |
---|---|---|
1.12.2.1 | long exposure of the oxidized enzyme to oxygen does not irreversibly inactivate the hydrogenase. In the reduced form the hydrogenase is irreveribly inactivated | Desulfovibrio vulgaris |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.12.2.1 | H2 + ferredoxin | requires the presence of cytochrome c3 for the reduction of ferredoxin | Megalodesulfovibrio gigas | H+ + reduced ferredoxin | - |
? | |
1.12.2.1 | H2 + ferricytochrome c3 | - |
Desulfovibrio desulfuricans | H+ + ferrocytochrome c3 | - |
? | |
1.12.2.1 | H2 + ferricytochrome c3 | - |
Desulfovibrio vulgaris | H+ + ferrocytochrome c3 | - |
? | |
1.12.2.1 | H2 + ferricytochrome c3 | - |
Megalodesulfovibrio gigas | H+ + ferrocytochrome c3 | - |
? | |
1.12.2.1 | H2 + ferricytochrome c3 | - |
Desulfovibrio desulfuricans Norway 4 | H+ + ferrocytochrome c3 | - |
? | |
1.12.2.1 | H2 + ferricytochrome c3 | - |
Desulfovibrio vulgaris Hildenborough | H+ + ferrocytochrome c3 | - |
? | |
1.12.2.1 | H2 + rubredoxin | requires the presence of cytochrome c3 for the reduction of rubredoxin | Megalodesulfovibrio gigas | H+ + reduced rubredoxin | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.12.2.1 | ? | x * 26000 + x * 62000 | Megalodesulfovibrio gigas |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.12.2.1 | cytochrome c3 | - |
Desulfovibrio desulfuricans | |
1.12.2.1 | cytochrome c3 | - |
Desulfovibrio vulgaris | |
1.12.2.1 | cytochrome c3 | requires the presence of cytochrome c3 for the reduction of ferredoxin, rubredoxin and cytochrome c3 | Megalodesulfovibrio gigas |