Literature summary extracted from

Ren, S.; Liu, H.; Licad, E.; Correia, M.A.
Expression of rat liver tryptophan 2,3-dioxygenase in Escherichia coli: structural and functional characterization of the purified enzyme (1996), Arch. Biochem. Biophys., 333, 96-102.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.13.11.52	expression in Escherichia coli	Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.11.52	L-Trp + O2	Rattus norvegicus	key regulatory enzyme, though irreversible degradation, controls the flux of tryptophan through physiologically relevant pathways	L-formylkynurenine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.52	Rattus norvegicus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.13.11.52	expression of a fully functional enzyme in Escherichia coli	Rattus norvegicus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.52	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.52	L-Trp + O2	-	Rattus norvegicus	L-formylkynurenine	-	?
1.13.11.52	L-Trp + O2	key regulatory enzyme, though irreversible degradation, controls the flux of tryptophan through physiologically relevant pathways	Rattus norvegicus	L-formylkynurenine	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)