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Literature summary extracted from
- A cryptic, microsomal-type arachidonate 12-lipoxygenase is tonically inactivated by oxidation-reduction conditions in cultured epithelial cells (1993), J. Biol. Chem., 268, 371-376.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.13.11.31 | membrane | bound to | Ovis aries | 16020 | - |
| 1.13.11.31 | microsome | enzyme is expressed in a cryptic, microsomal-type form in primary culture epithelial cells, this form of enzyme may be selectively regulated by changes in cellular oxidation-reduction conditions dependent on cytosolic levels of GSH versus lipid hydroperoxide | Ovis aries | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.11.31 | Ovis aries | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.13.11.31 | tracheal epithelium | - |
Ovis aries | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.11.31 | arachidonate + O2 | i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid | Ovis aries | (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate | - |
? |  |
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Release 2023.1 (January 2023)
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