BRENDA - Enzyme Database show

Characterization of arachidonate 12-lipoxygenase found in the liver of mongrel dog and its immunohistochemical localization in neutrophils

Reddy, G.R.; Ueda, N.; Suzuki, T.; Yamamoto, S.; Ishimura, K.; Kawada, N.; Mizoguchi, Y.; Tokushima J. Exp. Med. 42, 27-35 (1995)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.13.11.31
cytosol
-
Canis lupus familiaris
5829
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.13.11.31
Canis lupus familiaris
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.13.11.31
liver
enzyme activity is attributed predominantly to the neutrophils appearing in sinusoidal cavities rather than the non-parechymal cells
Canis lupus familiaris
-
1.13.11.31
neutrophil
-
Canis lupus familiaris
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.13.11.31
alpha-linolenic acid + O2
-
395422
Canis lupus familiaris
?
-
-
-
?
1.13.11.31
arachidonate + O2
i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid
395422
Canis lupus familiaris
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
395422
Canis lupus familiaris
?
1.13.11.31
gamma-linolenic acid + O2
-
395422
Canis lupus familiaris
10-hydroxy-octadeca-6Z,8E,12Z-trienoic acid
-
-
-
?
1.13.11.31
linoleic acid + O2
-
395422
Canis lupus familiaris
13(S)-hydroxy-9Z,11E-octadecadienoic acid
-
-
-
-
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.13.11.31
cytosol
-
Canis lupus familiaris
5829
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.13.11.31
liver
enzyme activity is attributed predominantly to the neutrophils appearing in sinusoidal cavities rather than the non-parechymal cells
Canis lupus familiaris
-
1.13.11.31
neutrophil
-
Canis lupus familiaris
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.13.11.31
alpha-linolenic acid + O2
-
395422
Canis lupus familiaris
?
-
-
-
?
1.13.11.31
arachidonate + O2
i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid
395422
Canis lupus familiaris
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
395422
Canis lupus familiaris
?
1.13.11.31
gamma-linolenic acid + O2
-
395422
Canis lupus familiaris
10-hydroxy-octadeca-6Z,8E,12Z-trienoic acid
-
-
-
?
1.13.11.31
linoleic acid + O2
-
395422
Canis lupus familiaris
13(S)-hydroxy-9Z,11E-octadecadienoic acid
-
-
-
-