BRENDA - Enzyme Database

Identification of a novel arachidonate 12-lipoxygenase in bovine tracheal epithelial cells distinct from leukocyte and platelet forms of the enzyme

Hansbrough, J.R.; Takahashi, Y.; Ueda, N.; Yamamoto, S.; Holtzman, M.J.; J. Biol. Chem. 265, 1771-1776 (1990) View publication on PubMed

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.13.11.31
cytosol
-
Bos taurus
5829
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
1.13.11.31
72000
-
x * 72000, SDS-PAGE
Bos taurus
Organism
EC Number
Organism
UniProt
Commentary
Textmining
1.13.11.31
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.13.11.31
leukocyte
-
Bos taurus
-
1.13.11.31
tracheal epithelium
-
Bos taurus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.13.11.31
0.3
-
epithelial enzyme
Bos taurus
1.13.11.31
0.7
-
leukocyte enzyme
Bos taurus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1.13.11.31
11,14,17-eicosatrienoic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
11,14-eicosadienoic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
4,7,10,13,16,19-docosahexaenoic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
5,8,11,14,17-eicosapentaenoic acid + O2
-
395404
Bos taurus
12-hydroxy-5,8,10,14,17-eicosapentaenoic acid
-
-
-
?
1.13.11.31
8,11,14-eicosatrienoic acid + O2
dihomo-gamma-linolenic acid
395404
Bos taurus
12-hydroxyeicosatrienoic acid
-
-
-
?
1.13.11.31
alpha-linolenic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
arachidonate + O2
i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid
395404
Bos taurus
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
395404
Bos taurus
?
1.13.11.31
gamma-linolenic acid + O2
i.e. 6,9,12-octadecatrienoic acid
395404
Bos taurus
10-hydroxy-octadeca-6Z,8E,12Z-trienoic acid
-
-
-
?
1.13.11.31
linoleic acid + O2
i.e. 9,12-octadecadienoic acid
395404
Bos taurus
13(S)-hydroxy-9Z,11E-octadecadienoic acid
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
1.13.11.31
?
x * 72000, SDS-PAGE
Bos taurus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
1.13.11.31
7.4
8
-
Bos taurus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.13.11.31
cytosol
-
Bos taurus
5829
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
1.13.11.31
72000
-
x * 72000, SDS-PAGE
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.13.11.31
leukocyte
-
Bos taurus
-
1.13.11.31
tracheal epithelium
-
Bos taurus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.13.11.31
0.3
-
epithelial enzyme
Bos taurus
1.13.11.31
0.7
-
leukocyte enzyme
Bos taurus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1.13.11.31
11,14,17-eicosatrienoic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
11,14-eicosadienoic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
4,7,10,13,16,19-docosahexaenoic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
5,8,11,14,17-eicosapentaenoic acid + O2
-
395404
Bos taurus
12-hydroxy-5,8,10,14,17-eicosapentaenoic acid
-
-
-
?
1.13.11.31
8,11,14-eicosatrienoic acid + O2
dihomo-gamma-linolenic acid
395404
Bos taurus
12-hydroxyeicosatrienoic acid
-
-
-
?
1.13.11.31
alpha-linolenic acid + O2
-
395404
Bos taurus
?
-
-
-
?
1.13.11.31
arachidonate + O2
i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid
395404
Bos taurus
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
395404
Bos taurus
?
1.13.11.31
gamma-linolenic acid + O2
i.e. 6,9,12-octadecatrienoic acid
395404
Bos taurus
10-hydroxy-octadeca-6Z,8E,12Z-trienoic acid
-
-
-
?
1.13.11.31
linoleic acid + O2
i.e. 9,12-octadecadienoic acid
395404
Bos taurus
13(S)-hydroxy-9Z,11E-octadecadienoic acid
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
1.13.11.31
?
x * 72000, SDS-PAGE
Bos taurus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
1.13.11.31
7.4
8
-
Bos taurus