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Literature summary extracted from
- The excreted beta-cyclopiazonate oxidocyclase isoenzymes from Penicillium clyclopium. II. Evidence for an ping-pong bi-bi mechanism from substrate inhibition studies (1979), Int. J. Biochem., 10, 61-65.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.21.99.1 | 2,6-dichlorophenolindophenol | competitive inhibition | Penicillium cyclopium |  |
| 1.21.99.1 | beta-Cyclopiazonate | - |
Penicillium cyclopium | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.21.99.1 | beta-cyclopiazonate + acceptor | Penicillium cyclopium | - |
alpha-cyclopiazonate + reduced acceptor | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.21.99.1 | Penicillium cyclopium | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 1.21.99.1 | beta-cyclopiazonate + acceptor = alpha-cyclopiazonate + reduced acceptor | ping-pong bi-bi mechanism | Penicillium cyclopium |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.21.99.1 | beta-cyclopiazonate + acceptor | - |
Penicillium cyclopium | alpha-cyclopiazonate + reduced acceptor | - |
? | |
| 1.21.99.1 | beta-cyclopiazonate + acceptor | acceptors: 2,6-dichlorophenolindophenol, cytochrome c, phenazine methosulfate, oxygen, cyclopiazonate is a microbial toxin | Penicillium cyclopium | alpha-cyclopiazonate + reduced acceptor | - |
? | |
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