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Literature summary extracted from

  • Kadlubar, F.F.; Mckee, E.M.; Ziegler, D.M.
    Reduced pyridine nucleotide-dependent N-hydroxy amine oxidase and reductase activities of hepatic microsomes (1973), Arch. Biochem. Biophys., 156, 46-57.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.1.10 additional information not inhibited by 0.1 mM KCN, NaN3, EDTA, CO and O2 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.7.1.10 microsome
-
 Sus scrofa
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.7.1.10 Sus scrofa
-
 microsomal multicomponent enzyme system consisting of NADH, cytochrome b5, cytochrome b5 reductase and a third unidentified protein, catalyzes reduction of hydroxylamine and a number of its mono- and disubstituted derivatives
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.7.1.10 kidney
-
 Sus scrofa
-
1.7.1.10 liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.1.10 hydroxylamine + NADH
-
 Sus scrofa NH3 + NAD+ + H2O
-
 ?
1.7.1.10 N,N-dimethylhydroxylamine + NADH
-
 Sus scrofa dimethylamine + NAD+ + H2O
-
 ?
1.7.1.10 N-hydroxyamphetamine + NADH
-
 Sus scrofa amphetamine + NAD+ + H2O
-
 ?
1.7.1.10 N-hydroxypiperidine + NADH
-
 Sus scrofa piperidine + NAD+ + H2O
-
 ?
1.7.1.10 N-methyl-N-benzyl-hydroxylamine + NADH
-
 Sus scrofa N-methylbenzylamine + NAD+ + H2O
-
 ?
1.7.1.10 N-methyl-N-n-octyl-hydroxylamine + NADH
-
 Sus scrofa N-methyl-n-octylamine + NAD+ + H2O
-
 ?
1.7.1.10 N-methylhydroxylamine + NADH
-
 Sus scrofa methylamine + NAD+ + H2O
-
 ?
1.7.1.10 phenylhydroxylamine + NADH
-
 Sus scrofa phenylamine + NAD+ + H2O
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.7.1.10 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.7.1.10 6.3
-
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.7.1.10 NADH
-
 Sus scrofa