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Literature summary extracted from

  • Segura-Aguilar, J.; Kaiser, R.; Lind, C.
    Separation and characterization of isoforms of DT-diaphorase from rat liver cytosol (1992), Biochim. Biophys. Acta, 1120, 33-42.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.6.5.2 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
1.6.5.2 Rattus norvegicus
-
 isoforms II, III, IV, V, VI and VII in liver
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.6.5.2 glycoprotein all 6 isoforms are glycoproteins Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
1.6.5.2 partial, isoforms Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.5.2 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.6.5.2 505
-
 isoform III, towards menadione Rattus norvegicus
1.6.5.2 634
-
 isoform IV, towards menadione Rattus norvegicus
1.6.5.2 1129
-
 isoform VII, towards menadione Rattus norvegicus
1.6.5.2 1186
-
 isoform V, towards menadione Rattus norvegicus
1.6.5.2 2228
-
 isoform II, towards menadione Rattus norvegicus
1.6.5.2 2459
-
 isoform VIb, towards menadione Rattus norvegicus
1.6.5.2 5860
-
 isoform VIa, towards menadione Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.5.2 2-methyl-1,4-naphthoquinone + NAD(P)H artificial acceptor, trivial name menadione Rattus norvegicus 2-methyl-1,4-naphthoquinol + NAD(P)+
-
 ?
1.6.5.2 2-methyl-3-phytyl-1,4-naphthoquinone + NAD(P)H trivial name vitamin K1 Rattus norvegicus 2-methyl-3-phytyl-1,4-naphthohydroquinone + NAD(P)+
-
 ?
1.6.5.2 benzo[a]pyrene 3,6-quinone + NAD(P)H
-
 Rattus norvegicus benzo[a]pyrene 3,6-quinol
-
 ?
1.6.5.2 cyclized-dopamine o-quinone + NAD(P)H
-
 Rattus norvegicus cyclized-dopamine o-hydroquinone + NADP+
-
 ?