Literature summary extracted from

Stephens, R.W.; Whittaker, V.K.
Calf thymus GMP reductase: control by XMP (1973), Biochem. Biophys. Res. Commun., 53, 975-981.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.7.1.7	IMP	0.05 mM, 25% inhibition, competitive vs. GMP	Bos taurus
1.7.1.7	additional information	not inhibited by ATP	Bos taurus
1.7.1.7	XMP	0.0005 mM, 89% inhibition	Bos taurus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.7.1.7	0.0014	-	GMP	-	Bos taurus
1.7.1.7	0.031	-	NADPH	-	Bos taurus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.7.1.7	90000	-	gel filtration	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.7.1.7	Bos taurus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.7.1.7	-	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.7.1.7	thymus	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.7.1.7	NADPH + guanosine 5'-phosphate	-	Bos taurus	NADP+ + inosine 5'-phosphate + NH3	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.7.1.7	7.5	-	-	Bos taurus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.7.1.7	NADPH	specific for	Bos taurus

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.7.1.7	0.00001	-	XMP	-	Bos taurus

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Release 2023.1 (January 2023)