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Literature summary extracted from

  • Townsend, D.; Lata, G.F.
    Purification of urate oxidase; a sex dependent enzyme from rat liver (1969), Arch. Biochem. Biophys., 135, 166-172.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.7.3.3 Repeated freezing and thawing has no effect Rattus norvegicus
1.7.3.3 urate oxidase from female rat livers is more stable than enzyme from male rat livers Rattus norvegicus
1.7.3.3 urea, 4 M, several h without loss of activity Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.3.3 CN-
-
 Rattus norvegicus
1.7.3.3 Cu2+
-
 Rattus norvegicus
1.7.3.3 glycerol
-
 Rattus norvegicus
1.7.3.3 sucrose
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.7.3.3 urate + O2 + H2O Rattus norvegicus
-
 5-hydroxyisourate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.7.3.3 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.7.3.3
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.7.3.3 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.7.3.3 9.35
-
 male rats Rattus norvegicus
1.7.3.3 15.3
-
 female Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
1.7.3.3 3°C, 0.15% sodium carbonate, several weeks, stable Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.3.3 urate + O2 + H2O
-
 Rattus norvegicus 5-hydroxyisourate + H2O2
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.7.3.3 8.5 9.3
-
 Rattus norvegicus