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Literature summary extracted from

  • Lohrer, H.; Krauth-Siegel, R.L.
    Purification and characterization of lipoamide dehydrogenase from Trypanosoma cruzi (1990), Eur. J. Biochem., 194, 863-869.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.4 1,3-bis(2-chloroethyl)-1-nitrourea after reduction of the oxidized form of enzyme to the two-electron-reduced state Trypanosoma cruzi

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.1.4 0.023
-
 NADH
-
 Trypanosoma cruzi
1.8.1.4 5
-
 Lipoamide
-
 Trypanosoma cruzi

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.8.1.4 55000
-
 2 * 55000, SDS-PAGE Trypanosoma cruzi

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.4 Trypanosoma cruzi
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.1.4
-
 Trypanosoma cruzi

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.4 epimastigote
-
 Trypanosoma cruzi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.4 dihydrolipoamide + NAD+
-
 Trypanosoma cruzi lipoamide + NADH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.8.1.4 dimer 2 * 55000, SDS-PAGE Trypanosoma cruzi

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.4 FAD
-
 Trypanosoma cruzi
1.8.1.4 NAD+
-
 Trypanosoma cruzi