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Literature summary extracted from

  • Rameh, L.E.; Tolias, K.F.; Duckworth, B.C.; Cantley, L.C.
    A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate (1997), Nature, 390, 192-196.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.149 ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate Homo sapiens
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.149 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.149 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.149 ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate poor substrate compared to 1-phosphatidyl-1D-myo-inositol 5-phosphate Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate
-
 ?
2.7.1.149 ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate
-
 Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?
2.7.1.149 ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate phosphorylation at the D-4 position Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?
2.7.1.149 ATP + dipalmitoyl-phosphatidyl-1D-myo-inositol 5-phosphate
-
 Homo sapiens ADP + dipalmitoyl-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?