BRENDA - Enzyme Database show

Human sulfite oxidase R160Q: identification of the mutation in a sulfite oxidase-deficient patient and expression characterization of the mutant enzyme

Garrett, R.M.; Johnson, J.L.; Graf, T.N.; Feigenbaum, A.; Rajagopalan, K.V.; Proc. Natl. Acad. Sci. USA 95, 6394-6398 (1998)

Data extracted from this reference:

Engineering
EC Number
Amino acid exchange
Commentary
Organism
1.8.3.1
R160Q
sulfite-oxidase deficient patient
Homo sapiens
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
1.8.3.1
Mo
-
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.8.3.1
sulfite + cytochrome c
Homo sapiens
genetic deficiency results in neurological abnormities
sulfate + reduced cytochrome c
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.8.3.1
Homo sapiens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.8.3.1
sulfite + cytochrome c
genetic deficiency results in neurological abnormities
393028
Homo sapiens
sulfate + reduced cytochrome c
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.8.3.1
heme
-
Homo sapiens
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.8.3.1
heme
-
Homo sapiens
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
1.8.3.1
R160Q
sulfite-oxidase deficient patient
Homo sapiens
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
1.8.3.1
Mo
-
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.8.3.1
sulfite + cytochrome c
Homo sapiens
genetic deficiency results in neurological abnormities
sulfate + reduced cytochrome c
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.8.3.1
sulfite + cytochrome c
genetic deficiency results in neurological abnormities
393028
Homo sapiens
sulfate + reduced cytochrome c
-
-
-
?