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Literature summary extracted from

  • Suzuki, K.
    Distribution of 4-nitroquinoline 1-oxide reductase in the mucosa of canine digestive tract (1978), Gann, 69, 229-235.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.7.1.9 cytosol most of the activity Canis lupus familiaris 5829
-

Organism

EC Number Organism UniProt Comment Textmining
1.7.1.9 Canis lupus familiaris
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.7.1.9 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+ 4-(hydroxyamino)quinoline N-oxide may be the active intermediate essential in the carcinogenic process of 4-nitroquinoline N-oxide Canis lupus familiaris
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.7.1.9 0.3
-
 activity in cytosol from mucous membrane of esophagus Canis lupus familiaris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.1.9 4-nitroquinoline N-oxide + NAD(P)H + H+
-
 Canis lupus familiaris 4-(hydroxyamino)quinoline N-oxide + NAD(P)+ + H2O
-
 ?