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Literature summary extracted from

  • De-Faria, M.H.; do-Nascimento, J.L.M.; Paes-de-Carvalho, R.
    Biochemical characterization of NADPH-diaphorase in the chick embryo retina: Stimulation by calcium ions and inhibition by arginine analogs (1995), Braz. J. Med. Biol. Res., 28, 252-255.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.99.1 EDTA
-
 Gallus gallus
1.6.99.1 EGTA
-
 Gallus gallus
1.6.99.1 L-N5-(1-iminoethyl)Orn 1 mM 63% inhibition Gallus gallus
1.6.99.1 monomethyl-L-Arg acetate 1 mM, 14% inhibition Gallus gallus
1.6.99.1 NG-nitro-L-Arg 3 mM, 53% inhibition Gallus gallus
1.6.99.1 Ngamma-monomethyl-L-Arg 1 mM, 14% inhibition Gallus gallus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.6.99.1 Ca2+ 2 mM CaCl2, 48% stimulates. The effect is reversed by 1 mM EGTA or EDTA Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
1.6.99.1 Gallus gallus
-
 diaphorase activity of nitric oxide synthase
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.99.1 embryo retina Gallus gallus
-
1.6.99.1 retina from embryo Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.99.1 NADPH + acceptor acceptor: nitroblue tetrazolium hydrochloride Gallus gallus NADP+ + reduced acceptor
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.6.99.1 nitric oxide synthase identical to Gallus gallus

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.99.1 NADPH
-
 Gallus gallus