Any feedback?
Literature summary extracted from
- Isolation of the iron-sulfur-containing polypeptides of NADH: oxidoreductase ubiquinone (1986), Methods Enzymol., 126, 360-369.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.1.1.2 | mitochondrion | - |
Bos taurus | 5739 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.2 | Iron | enzyme contains Fe-S clusters | Bos taurus |  |
| 7.1.1.2 | Iron | the NADH:ubiquinone oxidoreductase complex is composed of three distinct fragments: 1. IP: a water soluble Fe-S-protein that is composed of 5-6 polypeptides and contains four Fe-S clusters, 2. FP: a water-soluble Fe-S-flavoprotein that is composed of three polypeptides and contains FMN and two Fe-S clusters, 3. a water-insoluble fraction containing phospholipids and hydrophobic polypeptides | Bos taurus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.2 | Bos taurus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 7.1.1.2 | lipoprotein | the NADH:ubiquinone oxidoreductase complex is composed of three distinct fragments: 1. IP: a water soluble Fe-S-protein that is composed of 5-6 polypeptides and contains four Fe-S clusters, 2. FP: a water-soluble FeS-flavoprotein that is composed of three polypeptides and contains FMN and two FeS clusters, 3. a water-insoluble fraction containing phospholipids and hydrophobic polypeptides | Bos taurus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.1.1.2 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 7.1.1.2 | heart | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.2 | NADH + ubiquinone | - |
Bos taurus | NAD+ + ubiquinol | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.1.1.2 | More | the NADH:ubiquinone oxidoreductase complex is composed of three distinct fragments: 1. IP: a water soluble Fe-S-protein that is composed of 5-6 polypeptides and contains four Fe-S clusters, 2. FP: a water-soluble FeS-flavoprotein that is composed of three polypeptides and contains FMN and two FeS clusters, 3. a water-insoluble fraction containing phospholipids and hydrophobic polypeptides | Bos taurus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.2 | FMN | enzyme contains FMN | Bos taurus | |
| 7.1.1.2 | NADH | - |
Bos taurus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
