EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.1.2 | glutathione | inhibition of forward and reverse reaction in the presence of NADPH, no inhibition of forward reaction in the presence of NADH, 40% inhibition of reverse reaction, little or no inhibition in the absence of substrates | Bos taurus | |
1.6.1.2 | glutathione disulfide | strong, time dependent inhibition of thio-NADP+ reduction by NADH and acetylpyridine adenine dinucleotide reduction by NADPH, 50% inhibition after 40 min incubation in 26.7 mM glutathione disulfide, presence of NADPH accelerates inhibition 20fold | Bos taurus | |
1.6.1.2 | Phenylarsine oxide | 0.448 mM, 50% inhibition of acetylpyridine adenine dinucleotide reduction by NADPH after 1 min, 97% inhibition after 60 min, addition of glutathione restores about 50% of activity | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.6.1.2 | mitochondrial membrane | - |
Bos taurus | 31966 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.1.2 | Bos taurus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.1.2 | heart | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.1.2 | NADH + NADP+ | - |
Bos taurus | NAD+ + NADPH | - |
? | |
1.6.1.2 | NADH + thio-NADP+ | - |
Bos taurus | NAD+ + thio-NADPH | - |
r | |
1.6.1.2 | NADPH + oxidized 3-acetylpyridine adenine dinucleotide | - |
Bos taurus | NADP+ + reduced 3-acetylpyridine adenine dinucleotide | - |
r |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.6.1.2 | NAD+ | - |
Bos taurus | |
1.6.1.2 | NADH | - |
Bos taurus | |
1.6.1.2 | NADP+ | - |
Bos taurus | |
1.6.1.2 | NADPH | - |
Bos taurus |