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Literature summary extracted from

  • Okada, M.; Kawashima, S.; Imahori, K.
    Substrate binding characteristics of the active site of spermidine dehydrogenase from Serratia marcescens (1979), J. Biochem., 85, 1235-1243.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.99.6 1,3-diaminooctane
-
 Serratia marcescens
1.5.99.6 1,4-diaminooctane
-
 Serratia marcescens
1.5.99.6 1,6-diaminooctane
-
 Serratia marcescens
1.5.99.6 1,8-diaminooctane competitive inhibition Serratia marcescens

Organism

EC Number Organism UniProt Comment Textmining
1.5.99.6 Serratia marcescens
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.5.99.6 436
-
-
 Serratia marcescens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.99.6 N-alkylputrescine + electron acceptor
-
 Serratia marcescens ? + reduced electron acceptor
-
 ?
1.5.99.6 spermidine + electron acceptor
-
 Serratia marcescens 1,3-diaminopropane + DELTA1-pyrroline + reduced electron acceptor
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.99.6 7.5
-
 spermidine Serratia marcescens
1.5.99.6 7.5 10 triamines and tetramines Serratia marcescens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.5.99.6 0.0023
-
 1,8-diaminooctane
-
 Serratia marcescens
1.5.99.6 0.34
-
 1,6-diaminooctane does not inhibit the enzyme when spermidine is used as substrate Serratia marcescens
1.5.99.6 1
-
 1,3-diaminooctane
-
 Serratia marcescens
1.5.99.6 1.8
-
 1,4-diaminooctane does not inhibit the enzyme when spermidine is used as substrate Serratia marcescens