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Literature summary extracted from
- Spermidine dehydrogenase (Serratia marcescens) (1971), Methods Enzymol., 17B, 746-753.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.99.6 | p-chloromercuribenzoate | - |
Serratia marcescens |  |
| 1.5.99.6 | phenylhydrazine | - |
Serratia marcescens | |
| 1.5.99.6 | Quinacrine | - |
Serratia marcescens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.5.99.6 | additional information | - |
additional information | at optimal pH Km for spermidine less than 0.0001 mM | Serratia marcescens | |
| 1.5.99.6 | 0.05 | - |
spermine | - |
Serratia marcescens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.5.99.6 | 76000 | - |
- |
Serratia marcescens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.5.99.6 | Serratia marcescens | - |
- |
- |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.5.99.6 | 420 | - |
- |
Serratia marcescens |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.5.99.6 | -20°C, can be stored in supernatant solution for several weeks without loss of activity | Serratia marcescens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.99.6 | 3,3'-diaminodipropylamine + electron acceptor | - |
Serratia marcescens | ? + reduced electron acceptor | - |
? | |
| 1.5.99.6 | monoacetylspermidine + electron acceptor | - |
Serratia marcescens | ? + reduced electron acceptor | - |
? | |
| 1.5.99.6 | N,N'-di(aminopropyl)-propanediamine + electron acceptor | - |
Serratia marcescens | ? + reduced electron acceptor | - |
? | |
| 1.5.99.6 | spermidine + 2,6-dichlorophenolindophenol | - |
Serratia marcescens | 1,3-diaminopropane + DELTA1-pyrroline + reduced 2,6-dichlorophenolindophenol | - |
? | |
| 1.5.99.6 | spermidine + electron acceptor | - |
Serratia marcescens | 1,3-diaminopropane + DELTA1-pyrroline + reduced electron acceptor | - |
? | |
| 1.5.99.6 | spermidine + K3Fe(CN)6 | - |
Serratia marcescens | 1,3-diaminopropane + DELTA1-pyrroline + ferrocyanide | - |
? | |
| 1.5.99.6 | spermidine + phenazine methosulfate | - |
Serratia marcescens | 1,3-diaminopropane + DELTA1-pyrroline + reduced phenazine methosulfate | - |
? | |
| 1.5.99.6 | spermine + electron acceptor | - |
Serratia marcescens | ? + reduced electron acceptor | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.5.99.6 | 7.2 | - |
spermidine as substrate | Serratia marcescens |
| 1.5.99.6 | 8.8 | - |
spermine as substrate | Serratia marcescens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.99.6 | FAD | - |
Serratia marcescens | |
| 1.5.99.6 | iron-protoporphyrin IX | - |
Serratia marcescens | |
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