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Literature summary extracted from

  • Rao, V.V.; Tsai, M.J.; Pan, X.; Chang, Y.F.
    L-Pipecolic acid oxidation in rat: subcellular localization and developmental study (1993), Biochim. Biophys. Acta, 1164, 29-35.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.5.3.7 di-(2-ethylhexyl)phthalate 5 g per kg body weight, 500% activity enhancement in the peroxisomal fraction Rattus norvegicus
1.5.3.7 glucagon 3 mg per kg body weight, 150% activity enhancement in the mitochondrial fraction Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.3.7 antimycin A
-
 Rattus norvegicus
1.5.3.7 rotenone
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.3.7 mitochondrion matrix protein Rattus norvegicus 5739
-
1.5.3.7 peroxisome membrane-associated Rattus norvegicus 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.3.7 L-pipecolate + O2 Rattus norvegicus
-
 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 the product reacts with water to form 2-aminoadipate 6-semialdehyde ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.3.7 Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.3.7 brain white matter contains a more than 2-fold higher activity than cortex Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.3.7 L-pipecolate + O2
-
 Rattus norvegicus 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 the product reacts with water to form 2-aminoadipate 6-semialdehyde ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.3.7 8.5
-
 assay at Rattus norvegicus