Literature summary extracted from

Varalakshmi, K.; Savithri, H.S.; Rao, N.A.
Identification of amino acid residues essential for enzyme activity of sheep liver 5,10-methylenetetrahydrofolate reductase (1986), Biochem. J., 236, 295-298.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.5.1.20	diethyldicarbonate	20 mM NADP+ and 20 mM NAD+ partially protected the enzyme against inactivation whereas 20 mM nicotinamide gives complete protection	Ovis aries
1.5.1.20	additional information	residues essential for enzyme activity: arginine, histidine, tryptophan	Ovis aries
1.5.1.20	N-bromosuccinimide	inactivates the enzyme by modification of tryptophan	Ovis aries
1.5.1.20	Phenylglyoxal	-	Ovis aries

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.20	Ovis aries	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.5.1.20	liver	-	Ovis aries	-

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Release 2023.1 (January 2023)