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Literature summary extracted from

  • Peri, K.G.; Mackenzie, R.E.
    NAD(+)-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase: detection of the mRNA in normal murine tissues and transcriptional regulation of the gene in cell lines (1993), Biochim. Biophys. Acta, 1171, 281-287.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.5.1.15
-
 Mus musculus
1.5.1.15
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.1.15 mitochondrion
-
 Mus musculus 5739
-
1.5.1.15 mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.5.1.15 34000
-
-
 Mus musculus
1.5.1.15 34000
-
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH Mus musculus
-
 L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH Homo sapiens
-
 L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH Rattus norvegicus
-
 L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+ Mus musculus
-
 5,10-methenyl-tetrahydrofolate + NADH
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+ Homo sapiens
-
 5,10-methenyl-tetrahydrofolate + NADH
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+ Rattus norvegicus
-
 5,10-methenyl-tetrahydrofolate + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.15 Homo sapiens
-
-
-
1.5.1.15 Mus musculus
-
 murine cell lines NIH 3T3, Balb/C 3T3, Balb/C 3T3-SV-T2(SV40-transformed), C3H 10T1/2, YAC(Moloney virus transformed), PSI-2(a murine ecotropic packaging cell line)
-
1.5.1.15 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.15 adrenal cortex
-
 Rattus norvegicus
-
1.5.1.15 bone marrow
-
 Mus musculus
-
1.5.1.15 bone marrow
-
 Rattus norvegicus
-
1.5.1.15 embryo
-
 Mus musculus
-
1.5.1.15 fibroblast
-
 Mus musculus
-
1.5.1.15 fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH
-
 Mus musculus L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH
-
 Homo sapiens L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH
-
 Rattus norvegicus L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+
-
 Mus musculus 5,10-methenyl-tetrahydrofolate + NADH
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+
-
 Homo sapiens 5,10-methenyl-tetrahydrofolate + NADH
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+
-
 Rattus norvegicus 5,10-methenyl-tetrahydrofolate + NADH
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.5.1.15 methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
 Mus musculus
1.5.1.15 methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
 Homo sapiens
1.5.1.15 NMDMC
-
 Mus musculus