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Literature summary extracted from

  • Mejia, N.; Mackenzie, R.E.
    NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase in transformed cells is a mitochondrial enzyme (1988), Biochem. Biophys. Res. Commun., 155, 1-6.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.5.1.15 DNA sequencing Mus musculus
1.5.1.15 isolation of cDNA and the gene encoding the murine cytoplasmic methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase (DCS) Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.1.15 mitochondrion
-
 Mus musculus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.5.1.15 Mg2+
-
 Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.5.1.15 34000
-
 anti-NAD-dehydrogenase antiserum Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH Mus musculus
-
 L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+ Mus musculus
-
 5,10-methenyl-tetrahydrofolate + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.15 Mus musculus
-
 mouse, Ehrlich ascites tumor cells
-
1.5.1.15 Mus musculus
-
 cell lines YAC, P815
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.1.15 from ascites tumor cells Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.15 L-5,10-methenyl-tetrahydrofolate + NADH
-
 Mus musculus L-5,10-methylenetetrahydrofolate + NAD+
-
 r
1.5.1.15 L-5,10-methylenetetrahydrofolate + NAD+
-
 Mus musculus 5,10-methenyl-tetrahydrofolate + NADH
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.5.1.15 methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.15 NAD+
-
 Mus musculus