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Literature summary extracted from

  • Cogoni, A.; Farci, R.; Medda, R.; Rinaldi, A.; Floris, G.
    Amine oxidase from Lathyrus cicera and Phaseolus vulgaris: purification and properties (1989), Prep. Biochem., 19, 95-112.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.4.3.22 enzyme does not withstand lyophilization Phaseolus vulgaris
1.4.3.22 enzyme does not withstand lyophilization Lathyrus cicera

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.22 beta-Bromoethylamine
-
 Lathyrus cicera
1.4.3.22 beta-Bromoethylamine
-
 Phaseolus vulgaris
1.4.3.22 diethyldithiocarbamate
-
 Lathyrus cicera
1.4.3.22 diethyldithiocarbamate
-
 Phaseolus vulgaris
1.4.3.22 NaCN
-
 Lathyrus cicera
1.4.3.22 NaCN
-
 Phaseolus vulgaris
1.4.3.22 phenylhydrazine
-
 Lathyrus cicera
1.4.3.22 phenylhydrazine
-
 Phaseolus vulgaris
1.4.3.22 Semicarbazide
-
 Lathyrus cicera
1.4.3.22 Semicarbazide
-
 Phaseolus vulgaris

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.22 0.32
-
 putrescine
-
 Lathyrus cicera
1.4.3.22 7
-
 putrescine
-
 Phaseolus vulgaris

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.3.22 copper enzyme contains 0.082% copper Phaseolus vulgaris
1.4.3.22 copper enzyme contains 0.082% copper Lathyrus cicera

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.22 75000
-
 2 * 75000, SDS-PAGE Phaseolus vulgaris
1.4.3.22 75000
-
 2 * 75000, SDS-PAGE Lathyrus cicera
1.4.3.22 150000
-
 gel filtration Phaseolus vulgaris
1.4.3.22 150000
-
 gel filtration Lathyrus cicera

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Lathyrus cicera
-
-
-
1.4.3.22 Phaseolus vulgaris
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.4.3.22 glycoprotein 14% neutral sugar Phaseolus vulgaris
1.4.3.22 glycoprotein 14% neutral sugar Lathyrus cicera

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.22
-
 Phaseolus vulgaris
1.4.3.22
-
 Lathyrus cicera

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.22 seed
-
 Phaseolus vulgaris
-
1.4.3.22 seed
-
 Lathyrus cicera
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.22 6.7
-
-
 Phaseolus vulgaris
1.4.3.22 50.8
-
-
 Lathyrus cicera

Storage Stability

EC Number Storage Stability Organism
1.4.3.22 -20°C, pH 7, indefinitely stable Phaseolus vulgaris
1.4.3.22 -20°C, pH 7, indefinitely stable Lathyrus cicera

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.22 1,4-diaminobutane + H2O + O2
-
 Phaseolus vulgaris 4-aminobutanal + NH3 + H2O2
-
 ?
1.4.3.22 1,4-diaminobutane + H2O + O2
-
 Lathyrus cicera 4-aminobutanal + NH3 + H2O2
-
 ?
1.4.3.22 1,5-diaminopentane + H2O + O2
-
 Phaseolus vulgaris 5-aminopentanal + NH3 + H2O2
-
 ?
1.4.3.22 1,5-diaminopentane + H2O + O2
-
 Lathyrus cicera 5-aminopentanal + NH3 + H2O2
-
 ?
1.4.3.22 1,6-diaminohexane + H2O + O2
-
 Phaseolus vulgaris 6-aminohexanal + NH3 + H2O2
-
 ?
1.4.3.22 1,6-diaminohexane + H2O + O2
-
 Lathyrus cicera 6-aminohexanal + NH3 + H2O2
-
 ?
1.4.3.22 1,7-diaminoheptane + H2O + O2
-
 Phaseolus vulgaris 7-aminoheptanal + NH3 + H2O2
-
 ?
1.4.3.22 1,7-diaminoheptane + H2O + O2
-
 Lathyrus cicera 7-aminoheptanal + NH3 + H2O2
-
 ?
1.4.3.22 agmatine
-
 Phaseolus vulgaris ?
-
 ?
1.4.3.22 agmatine
-
 Lathyrus cicera ?
-
 ?
1.4.3.22 p-dimethylaminomethylbenzylamine + H2O + O2
-
 Phaseolus vulgaris p-dimethylaminomethylbenzaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 p-dimethylaminomethylbenzylamine + H2O + O2
-
 Lathyrus cicera p-dimethylaminomethylbenzaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 RCH2NH2 + H2O + O2
-
 Phaseolus vulgaris RCHO + NH3 + H2O2
-
 ?
1.4.3.22 RCH2NH2 + H2O + O2
-
 Lathyrus cicera RCHO + NH3 + H2O2
-
 ?
1.4.3.22 spermidine + H2O + O2
-
 Phaseolus vulgaris ?
-
 ?
1.4.3.22 spermidine + H2O + O2
-
 Lathyrus cicera ?
-
 ?
1.4.3.22 spermine + H2O + O2
-
 Phaseolus vulgaris ?
-
 ?
1.4.3.22 spermine + H2O + O2
-
 Lathyrus cicera ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.22 dimer 2 * 75000, SDS-PAGE Phaseolus vulgaris
1.4.3.22 dimer 2 * 75000, SDS-PAGE Lathyrus cicera

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.22 7
-
-
 Lathyrus cicera
1.4.3.22 7.5
-
-
 Phaseolus vulgaris

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.22 pyrroloquinoline quinone enzyme may contain pyrroloquinoline-quinione as prosthetic group Phaseolus vulgaris
1.4.3.22 pyrroloquinoline quinone enzyme may contain pyrroloquinoline-quinione as prosthetic group Lathyrus cicera

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.22 0.00004
-
 phenylhydrazine
-
 Phaseolus vulgaris
1.4.3.22 0.00006
-
 phenylhydrazine
-
 Lathyrus cicera
1.4.3.22 0.0027
-
 beta-Bromoethylamine
-
 Phaseolus vulgaris
1.4.3.22 0.003
-
 Semicarbazide
-
 Phaseolus vulgaris
1.4.3.22 0.0063
-
 Semicarbazide
-
 Lathyrus cicera
1.4.3.22 0.007
-
 beta-Bromoethylamine
-
 Lathyrus cicera
1.4.3.22 0.07
-
 diethyldithiocarbamate
-
 Lathyrus cicera
1.4.3.22 0.09
-
 diethyldithiocarbamate
-
 Phaseolus vulgaris
1.4.3.22 0.3
-
 NaCN
-
 Lathyrus cicera
1.4.3.22 0.83
-
 NaCN
-
 Phaseolus vulgaris