EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.4.1.3 | ADP | - |
Rattus norvegicus | |
1.4.1.3 | ADP | - |
Bos taurus | |
1.4.1.3 | ADP | 1 mM, approx. 2fold activation of membrane-bound liver enzyme | Sus scrofa | |
1.4.1.3 | ATP | - |
Rattus norvegicus | |
1.4.1.3 | ATP | - |
Bos taurus | |
1.4.1.3 | ATP | approx. 1.5fold activation of membrane-bound liver enzyme | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.4.1.3 | ATP | - |
Bos taurus | |
1.4.1.3 | ATP | membrane-bound enzyme form, inhibition of microtubule-binding activity | Sus scrofa | |
1.4.1.3 | GTP | - |
Bos taurus | |
1.4.1.3 | GTP | - |
Rattus norvegicus | |
1.4.1.3 | GTP | membrane-bound liver enzyme, complete inhibition | Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.4.1.3 | membrane | peripheral membrane protein | Sus scrofa | 16020 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.4.1.3 | 50000 | - |
6 * 50000, membrane-bound liver enzyme, SDS-PAGE | Sus scrofa |
1.4.1.3 | 330000 | - |
membrane-bound liver enzyme, velocity sedimentation on sucrose density gradient | Sus scrofa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.1.3 | Bos taurus | - |
- |
- |
1.4.1.3 | Rattus norvegicus | - |
- |
- |
1.4.1.3 | Sus scrofa | - |
membrane-bound enzyme exhibits microtubule-binding activity | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.4.1.3 | affinity-purified | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.4.1.3 | brain | - |
Rattus norvegicus | - |
1.4.1.3 | brain | - |
Sus scrofa | - |
1.4.1.3 | brain | - |
Bos taurus | - |
1.4.1.3 | liver | - |
Rattus norvegicus | - |
1.4.1.3 | liver | - |
Sus scrofa | - |
1.4.1.3 | liver | - |
Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.4.1.3 | 4.6 | - |
membrane-bound liver enzyme | Sus scrofa |
1.4.1.3 | 17.8 | - |
liver enzyme | Rattus norvegicus |
1.4.1.3 | 34 | - |
liver enzyme | Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.1.3 | L-glutamate + H2O + NAD(P)+ | - |
Rattus norvegicus | 2-oxoglutarate + NH3 + NAD(P)H | - |
r | |
1.4.1.3 | L-glutamate + H2O + NAD(P)+ | - |
Sus scrofa | 2-oxoglutarate + NH3 + NAD(P)H | - |
r | |
1.4.1.3 | L-glutamate + H2O + NAD(P)+ | - |
Bos taurus | 2-oxoglutarate + NH3 + NAD(P)H | - |
r |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.4.1.3 | hexamer | 6 * 50000, membrane-bound liver enzyme, SDS-PAGE | Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.1.3 | 0.76 | - |
ATP | inhibition of microtubules to membrane-bound liver enzyme | Sus scrofa |