Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tanaka, K.; Miller, E.M.; Isselbacher, K.J.
    Hypoglycin A: a specific inhibitor of isovaleryl CoA dehydrogenase (1971), Proc. Natl. Acad. Sci. USA, 68, 20-24.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.8.4 alpha-keto-methylenecyclopropylpropionic acid
-
 Rattus norvegicus
1.3.8.4 hypoglycin inhibits, induces isovaleric acidemia when administered in experimental animals Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.4 mitochondrion
-
 Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.8.4 isovaleryl-CoA + acceptor Rattus norvegicus
-
 3-methylcrotonyl-CoA + reduced acceptor
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.4 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.4 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.4 isovaleryl-CoA + acceptor
-
 Rattus norvegicus 3-methylcrotonyl-CoA + reduced acceptor
-
 ?
1.3.8.4 isovaleryl-CoA + acceptor acceptors: electron-transfer flavoprotein, phenazine methosulfate Rattus norvegicus 3-methylcrotonyl-CoA + reduced acceptor
-
 ?