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Literature summary extracted from
- Enzymatic oxidation of bilirubin by intestinal mucosa (1987), Biochim. Biophys. Acta, 923, 268-274.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.3.5 | albumin | - |
Rattus norvegicus | |
| 1.3.3.5 | KCl | 50 mM, 40% inhibition | Rattus norvegicus |  |
| 1.3.3.5 | KCN | 30 mM, 78% inhibition | Rattus norvegicus | |
| 1.3.3.5 | MgCl2 | 50 mM, 52% inhibition | Rattus norvegicus | |
| 1.3.3.5 | NaCl | 50 mM, 17% inhibition | Rattus norvegicus | |
| 1.3.3.5 | NAD+ | 1 mM, 66% inhibition | Rattus norvegicus | |
| 1.3.3.5 | NADH | 1 mM, 72% inhibition | Rattus norvegicus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.3.3.5 | 0.077 | - |
bilirubin | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.3.3.5 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.3.5 | copper | 2 Cu2+ per protein molecule | Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.3.3.5 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.3.3.5 | small intestine mucosa | maximum activity in jejunum | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.3.3.5 | 0.00051 | - |
enzyme activity in small intestine | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.3.5 | bilirubin + O2 | - |
Rattus norvegicus | biliverdin + H2O | biliverdin + colourless diazo-negative compounds, including propentdyopents | ? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.3.3.5 | 40 | - |
- |
Rattus norvegicus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.3.3.5 | 100 | - |
5 min, complete inactivation | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.3.3.5 | 9 | - |
- |
Rattus norvegicus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.3.3.5 | 8 | 10 | at pH 8.0 and 10.0: about 30% of maximum activity | Rattus norvegicus |
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Release 2023.1 (January 2023)
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