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Literature summary extracted from

  • Birchfield, N.B.; Casida, J.E.
    Protoporphyrinogen oxidase: high affinity tetrahydrophthalimide radioligand for the inhibitor/herbicide-binding site in mouse liver mitochondria (1996), Chem. Res. Toxicol., 9, 1135-1139.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.3.4 N-(4-chloro-2-fluoro-5-(propargyloxy)phenyl)-3,4,5,6-tetrahydrophthalimide S-23142, reversible, Kd: 0.41 nM Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.3.4 mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.4 protoporphyrinogen-IX + 3 O2 Mus musculus penultimate step of heme and chlorophyll biosynthesis protoporphyrin-IX + 3 H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.4 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.4 liver
-
 Mus musculus
-

Storage Stability

EC Number Storage Stability Organism
1.3.3.4 -80°C, after freezing in liquid nitrogen, no loss of activity within 30 days Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.4 protoporphyrinogen-IX + 3 O2
-
 Mus musculus protoporphyrin-IX + 3 H2O2
-
 ?
1.3.3.4 protoporphyrinogen-IX + 3 O2 penultimate step of heme and chlorophyll biosynthesis Mus musculus protoporphyrin-IX + 3 H2O2
-
 ?