Literature summary extracted from

Kohno, H.; Furukawa, T.; Tokunaga, R.; Taketani, S.; Yoshinaga, T.
Mouse coprophorphyrinogen oxidase is a copper-containing enzyme: expression in E. coli and site-directed mutagenesis (1996), Biochim. Biophys. Acta, 1292, 156-162.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.3.3.3	expression in Escherichia coli	Mus musculus

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.3.3.3	H158A	complete loss of activity, decreased stability, no copper content	Mus musculus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.3.3.3	0.047	-	Coproporphyrinogen-III	-	Mus musculus

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.3.3.3	Cu2+	1.05 atoms per enzyme	Mus musculus
1.3.3.3	Fe2+	trace amounts	Mus musculus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.3.3.3	37000	-	x * 37000, SDS-PAGE	Mus musculus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.3.3.3	coproporphyrinogen-III + O2 + 2 H+	Mus musculus	-	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.3.3	Mus musculus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.3.3.3	to homogeneity, recombinant enzyme	Mus musculus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.3.3.3	0.28	-	-	Mus musculus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.3.3	coproporphyrinogen-III + O2 + 2 H+	-	Mus musculus	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.3.3.3	?	x * 37000, SDS-PAGE	Mus musculus

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Release 2023.1 (January 2023)