Literature summary extracted from

Kohno, H.; Furukawa, T.; Yoshinaga, T.; Tokunaga, R.; Taketani, S.
Coproporhyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid differentiation (1993), J. Biol. Chem., 268, 21359-21363.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.3.3.3	expression in Cos-1 cells	Bos taurus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.3.3.3	mitochondrion	-	Mus musculus	5739	-
1.3.3.3	mitochondrion	-	Bos taurus	5739	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.3.3.3	37000	-	x * 37000, SDS-PAGE	Mus musculus
1.3.3.3	37000	-	x * 37000, SDS-PAGE	Bos taurus
1.3.3.3	74000	-	gel filtration	Bos taurus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.3.3.3	coproporphyrinogen-III + O2 + 2 H+	Mus musculus	-	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?
1.3.3.3	coproporphyrinogen-III + O2 + 2 H+	Bos taurus	-	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.3.3	Bos taurus	-	-	-
1.3.3.3	Mus musculus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.3.3.3	to homogeneity, chromatography steps	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.3.3.3	cell culture	-	Mus musculus	-
1.3.3.3	erythroleukemia cell	-	Mus musculus	-
1.3.3.3	liver	-	Mus musculus	-
1.3.3.3	liver	-	Bos taurus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.3.3.3	0.72	-	-	Bos taurus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.3.3	coproporphyrinogen-III + O2 + 2 H+	-	Mus musculus	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?
1.3.3.3	coproporphyrinogen-III + O2 + 2 H+	-	Bos taurus	protoporphyrinogen-IX + 2 CO2 + 2 H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.3.3.3	?	x * 37000, SDS-PAGE	Mus musculus
1.3.3.3	?	x * 37000, SDS-PAGE	Bos taurus

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Release 2023.1 (January 2023)