Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Meinhardt, S.W.; Glass, T.L.
    Characterization of the NADH dehydrogenase and fumarate reductase of Fibrobacter succinogenes subsp. succinogenes S85 (1994), Arch. Microbiol., 162, 329-334.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.1.6 KCl can repace for NaCl Fibrobacter succinogenes
1.3.1.6 NaCl required for full activity, about 10fold activation at 150 mM Fibrobacter succinogenes

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.6 2-n-heptyl-4-hydroxyquinoline-N-oxide strong inhibitor Fibrobacter succinogenes
1.3.1.6 rotenone
-
 Fibrobacter succinogenes

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.1.6 membrane
-
 Fibrobacter succinogenes 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.6 fumarate + NADH + H+ Fibrobacter succinogenes realizes formation of succinate from oxalacetate succinate + NAD+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.6 Fibrobacter succinogenes
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.1.6 0.2 0.4
-
 Fibrobacter succinogenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.6 fumarate + NADH + H+
-
 Fibrobacter succinogenes succinate + NAD+
-
 ?
1.3.1.6 fumarate + NADH + H+ realizes formation of succinate from oxalacetate Fibrobacter succinogenes succinate + NAD+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.1.6 6
-
 in presence of NaCl, without NaCl maximum activity below pH 5 Fibrobacter succinogenes

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.3.1.6 5.5 7 in presence of NaCl Fibrobacter succinogenes

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.6 NADH
-
 Fibrobacter succinogenes

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.3.1.6 0.0006
-
 2-n-heptyl-4-hydroxyquinoline-N-oxide
-
 Fibrobacter succinogenes
1.3.1.6 0.001
-
 rotenone
-
 Fibrobacter succinogenes