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Literature summary extracted from

  • Aue, B.J.; Deibel, R.H.
    Fumarate reductase activity of Streptococcus faecalis (1967), J. Bacteriol., 93, 1770-1776.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.1.6 alanine
-
 Enterococcus faecalis
1.3.1.6 glycine
-
 Enterococcus faecalis
1.3.1.6 histidine
-
 Enterococcus faecalis

General Stability

EC Number General Stability Organism
1.3.1.6 stabilized against air oxidation with 10 mM thioglycollate Enterococcus faecalis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.6 citraconate slight inhibition Enterococcus faecalis
1.3.1.6 iodoacetate slight inhibition Enterococcus faecalis
1.3.1.6 malonate slight inhibition Enterococcus faecalis
1.3.1.6 p-chloromercuribenzoate slight inhibition Enterococcus faecalis
1.3.1.6 succinate slight inhibition Enterococcus faecalis
1.3.1.6 trans-, trans muconate slight inhibition Enterococcus faecalis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.6 0.2
-
 FMNH2
-
 Enterococcus faecalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.6 fumarate + NADH + H+ Enterococcus faecalis
-
 succinate + NAD+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.6 Enterococcus faecalis
-
-
-

Oxidation Stability

EC Number Oxidation Stability Organism
1.3.1.6 sensitive to air oxidation, loss of activity Enterococcus faecalis

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.6
-
 Enterococcus faecalis

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.1.6 0.23
-
 in presence of 10 mM thioglycolate Enterococcus faecalis

Storage Stability

EC Number Storage Stability Organism
1.3.1.6 stable in lyophylized whole cells Enterococcus faecalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.6 fumarate + FMNH2
-
 Enterococcus faecalis succinate + FMN
-
 r
1.3.1.6 fumarate + NADH + H+
-
 Enterococcus faecalis succinate + NAD+
-
 ?
1.3.1.6 fumarate + NADH + H+ FMNH2 serves as cofactor Enterococcus faecalis succinate + NAD+
-
 ir
1.3.1.6 maleate + NADH
-
 Enterococcus faecalis succinate + NAD+
-
 ir
1.3.1.6 mesaconate + NADH
-
 Enterococcus faecalis methylsuccinate + NAD+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.1.6 7.4
-
-
 Enterococcus faecalis

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.3.1.6 5 8
-
 Enterococcus faecalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.6 FMNH2
-
 Enterococcus faecalis
1.3.1.6 NADH
-
 Enterococcus faecalis