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Literature summary extracted from

  • Nagi, M.N.; Prasad, M.R.; Cook, L.; Cinti, D.
    Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase (1983), Arch. Biochem. Biophys., 226, 50-64.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.1.8 microsome
-
 Rattus norvegicus
-
-
1.3.1.38 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.8 Rattus norvegicus
-
 separation in NADPH-specific short-chain enoyl-CoA reductase and NAD(P)H-dependent long-chain enoyl-CoA reductase
-
1.3.1.8 Rattus norvegicus
-
 no information in the literature concerning reduction of cis-2-enoyl-CoA substrates, thus classification of rat enzyme according to EC 1.3.1.8 or EC 1.3.1.38 impossible
-
1.3.1.38 Rattus norvegicus
-
 no information in the literature concerning reduction of cis-2-enoyl-CoA substrates, thus classification of rat enzyme according to EC 1.3.1.8 or EC 1.3.1.38 not yet possible
-
1.3.1.44 Rattus norvegicus
-
 rat hepatic microsomal trans-2-enoyl-CoA reductases with cofactor requirement (NADH or NADPH) depending on chain length of substrates are characterized. Since no cis-2-enoyl-CoA compounds are tested as substrates a classification according to EC 1.3.1.8, EC 1.3.1.38 or EC 1.3.1.44 is impossible
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.8 liver
-
 Rattus norvegicus
-
1.3.1.38 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.8 2-trans-hexadecenoyl-CoA + NADPH
-
 Rattus norvegicus hexadecanoyl CoA + NADP+
-
 ?
1.3.1.8 2-trans-hexenoyl-CoA + NAD(P)H
-
 Rattus norvegicus hexanoyl-CoA + NADP+
-
 ?
1.3.1.8 additional information NADPH specific trans-enoyl-CoA reductases isolated from rat liver microsomes and mitochondria impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates Rattus norvegicus ?
-
 ?
1.3.1.38 additional information NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates Rattus norvegicus ?
-
 ?
1.3.1.44 additional information rat hepatic microsomal long-chain and short-chain trans-2-enoyl-CoA reductases with cofactor requirement (NADH or NADPH) depending on substrate chain length are characterized. Since no cis-2-enoyl-CoA compounds are tested as substrates a classification according to EC 1.3.1.8, EC 1.3.1.38 or EC 1.3.1.44 is impossible Rattus norvegicus ?
-
 ?
1.3.1.44 trans-2-hexadecenoyl-CoA + NADH
-
 Rattus norvegicus hexadecanoyl-CoA + NAD+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.8 NADPH inactive with NADH Rattus norvegicus
1.3.1.44 NADPH rat hepatic microsomal trans-2-enoyl-CoA reductases with cofactor requirement (NADH or NADPH) depending on chain length of substrates are characterized. Since no cis-2-enoyl-CoA substances are tested as substrates a classification according to EC 1.3.1.8, EC 1.3.1.38 or EC 1.3.1.44 is impossible Rattus norvegicus